How does meth work in the brain? The basic workings of meth’s psychoactive action in the central nervous system are described in this colorful infographic.


The Effects of Meth on the Body Infographic - Addicaid

How does meth work in the brain?

The basic workings of methamphetamine’s psychoactive action in the central nervous system are as follows:

1. Meth disrupts the dopamine neurotransmitter system.

2. Meth causes excess release of dopamine.

3. Meth overwhelms the process of reuptake.

4. Meth overwhelms the process of enzyme breakdown.

5. Meth causes dopamine to leak out of vesicles.

Dopamine regulates feelings of pleasure.

Dopamine affects control of movement, cognition, motivation, and reward.

High levels of free dopamine in the brain enhance mood and increase body movement.

Meth affects nucleus accumbens by increasing the release of dopamine.

How Addictive Is Meth?

Meth is HIGHLY addictive. Chronic use of stimulants like methamphetamines affect dopaminergic neurons in limbic reward system structures such as the VTA and nucleus accumbens, involved in reward, motivation, the experience of pleasure, and motor function. These effects underlie addiction.

Is Damage Caused By Meth Permanent ?

Permanent damage meth can cause: brain damage, cancer, immune system damage, kidney failure, liver failure, motor activity impairment, premature osteoporosis, & psychological problems.

What Are the Effects of Meth Addiction?

Effects on health: chronic illnesses, immune system damage, malnutrition, & permanent brain damage.

Effects on work: easily distracted, losing sense of time, no shows at work, & unemployment.

Effects on self esteem: difficulty communicating with others, lack of self-esteem, permanent psychological problem, & poor coping mechanisms.

Effects on relationships: break ups, decreased involvement of social life, estrangement, lack of trust.


If you or someone you know is struggling with addiction, take the first step towards recovery with the free Addicaid app for iPhone Android to join the recovery community today.

 [ht: Addiction Blog]

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